Publications

2026

243. C. Chang, M. Jeziored, Q. Yang, E. Bonder, H. Yan, J. Etchegaray, F. Zhang*

Designer RNA Nanostructures co-Transcribed and Self-assembled inside Human Cell Nuclei

Nature Communications, 17, Article no. 1055 (2026)

2025

242. X. Tu, L. Yu, L. Zhao, X.Qi, Y. Xu, H. Yan

Single-Stranded RNA Origami Remodels Macrophage to Promote the Synergistic Antitumor Effect with 5-Fluorouracil in Pancreatic Cancer

JACS Au, 5, 5758–5769 (2025)

241. G. B. M. Wisna, D. Sukhareva, J. Zhao, D. Satyabola, H. Yan*, R. F. Hariadi*

High-speed 3D DNA PAINT and Unsupervised Clustering for Unlocking 3D DNA Origami Cryptography

Nature Communications, 16, Article no. 11514 (2025)

240. P. Xia, D. Satyabola, N. K. Bamrah, Md A. R. Laska, A. Al Mamun, X. Zhou, G. B. M. Wisna, Y. Zhang, A. Ikbal, A. Kemeklis, A. E. Krylova, R. F. Hariadi, H. Yan*, C. Wang

DNA Helix Bundle-Encoded Multi-bit Information Readout by Sapphire-supported Nanopores

Advanced Functional Materials. doi: 0.1002/adfm.202523998

239. X. Jing, N. Kronebert, A. Peil, B. Renz, L. Ding, T. Heil, K. Hipp, P. A. van Aken, H. Yan, N. Liu*

DNA Moire Superlattices

Nature Nanotechnology 20, 1464–1472 (2025).

238. R. Zheng, A. Prasad, D. Satyabola, Y. Xu, H. Yan*

DNA-templated spatially controlled proteolysis targeting chimera for CyclinD1-CDK4/6 complex protein degradation

J. Am. Chem. Soc., 147, 29742-29755 (2025).

237. H. Liu, N. Liu*, H. Yan*

Programming Precise Nanoparticle Patterns

Nature Materials, 24,1166-1167 (2025).

236. T. Yip, X. Tu, X. Qi, H. Yan*, Y. Chang*

Adjuvanted RNA Origami- A Tunable Peptide Assembly Platform for Constructing Cancer Nanovaccines

Vaccines, 13 (6), 560.

235. S. Fan, S. Wang, L. Ding, T. Speck, H. Yan*, S. Nussberger*, N. Liu*

Morphology remodelling and membrane channel formation in synthetic cells via reconfigurable DNA nanorafts

Nature Materials, 24, 278-286 (2025).

2024

234. C. Zhang*, R. Wu, F. Sun, Y. Lin, Y. Zhang, Y. Liang, Y. Chen., L. Liu*, Q. Ouyang*, L. Qian*, H. Yan*.

Parallel DNA Storage by Programming and Printing Epigenetic Bits

Nature, 634, 824-832 (2024).

233. L. Yu, L. Chen, D. Satyabola, A. Prasad, H. Yan*

NucleoCraft: The art of stimuli-responsive precision in DNA and RNA bioengineering

BME Frontiers. 10.34133/bmef.0050

(2024).

232. D. Satyabola, A. Prasad, H. Yan*, X. Zhou*

Bioinspired photonic systems directed by designer DNA nanostructures

ACS Applied Optical Materials. doi.org/10.1021/acsaom.4c00103

(2024).

231. P. Zhan, J. Yang, L. Ding, X. Jing, K. Hipp, S. Nussberger, H. Yan, N. Liu*

3D DNA origami pincers that multitask on giant unilamellar vesicle

Science Advances, 10, eadn8903 (2024).

230. H. Liu, M. Matthies, J. Russo, L. Rovigatti, R. Narayanan, T. Diep, D. McKeen, O. Gang, N. Stephanopoulos, F. Sciortino, H. Yan, F. Romano, P. Sulc*

Inverse Design of a Pyrochlore Lattice of DNA Origami Through Model-driven Experiments

Science, 384, 776-781 (2024).

229. Y. Wang, H. Wang, Y. Li, C. Yang, Y. Tang, X. Lu, J. Fan, W. Tang, Y. Shang, H. Yan*, J. Liu*, B. Ding*

Chemically Conjugated Branched Staples for Super-DNA Origami

J. Am. Chem. Soc., 146, 4178-4186 (2024).

228. T. Yip, X. Qi, H. Yan*, Y. Chang*

RNA Origami Functions as a Self-adjuvanted Nanovaccine Platform for Cancer Immunotherapy

ACS Nano, 18, 4056-4067 (2024).

2023

227. R.P. Narayanan, A. Prasad, A. Buchberger, L. Zhou, J. Bernal-Chanchavac, T. MacCulloch, N.E. Fahmi, H. Yan, F. Zhang M.J. Webber*, N. Stephanopoulos*

High-Affinity Host–Guest Recognition for Efficient Assembly and Enzymatic Responsiveness of DNA Nanostructures

Small, 230785 (2023).

226. C. Simmons, H. Skyler, P. Sulc, N. Stephanopoulos*, H. Yan*

Site-specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-assembled Three-dimensional DNA Crystals

J. Am. Chem. Soc., 145, 26075-26085 (2023).

225. L. Yu, H. Yan*

DNA-based Computation for Multiple Biomarkers.

Nature Biomedical Engineering 7, 1535-1536 (2023).

224. L. Yu, Y. Xu, M. Al-Amin, S. Jiang, M. Sample, A. Prasad, N. Stephanopoulos, P. Sulc, H. Yan*

CytoDirect: a Nucleic Acid Nanodevice for Specific and Efficient Delivery of Functional Payloads to the Cytoplasm.

J. Am. Chem. Soc., 145, 27336-27347 (2023).

223. J. Yang, K. Jahnke, L. Xin, X. Jing, P. Zhan, A. Peil, A. Griffo, M. Skugor, D. Yang, S. Fan, K. Gopfrich*, H. Yan*, P. Wang*, N. Liu*

Modulating Lipid Membrane Morphology by Dynamic DNA Origami Networks

Nano Letters, 23, 6330-6336 (2023).

222. K. Dai, C. Gong, Y. Xu, F. Ding, X. Qi, X. Tu, L. Yu, X. Liu, J. Li, C. Fan, H. Yan*, G. Yao*

Single-Stranded RNA Origami-based Epigenetic Immunomodulation

Nano Letters 23, 7188-7196 (2023).

221. K. Dai, Y. Xu, Y. Yang, J. Shen, X. Liu, X. Tu, L. Yu, X. Qi, J. Li, L. Wang, X. Zuo, Y. Liu*, H. Yan*, C. Fan*, G. Yao*

Edge Length-Programmed Single-Stranded RNA Origami for Predictive Innate Immune Activation and Therapy

J. Am. Chem. Soc., 145, 17112-17124 (2023).

220. Y. Tang, H. Liu, Q. Wang, X. Qi, L. Yu, P. Sulc, F. Zhang, H. Yan*, S. Jiang*

DNA Origami Tessellations

J. Am. Chem. Soc., 145, 13858-13868 (2023).

2022

219. D. Fu, R. P. Narayanan, A. Prasad, F. Zhang, D. Williams, J. S. Schreck, H. Yan*, J. Reif*.

Automated Design of 3D DNA Origami with Non-rasterized 2D Curvature

Science Advances, 8, eade445 (2022).

218. X. Zhou', D. Satyabola, H. Liu, S. Jiang, X. Qi, L. Yu, S. Lin, Y. Liu, N.W. Woodbury*, H. Yan*

Two-Dimensional Excitonic Networks Directed by DNA Templates as an Efficient Model Light-Harvesting and Energy Transfer System

Angew. Chem. Int. Ed. 61, e2022112 (2022).

217. R. P. Narayanan, J. Procyk, P. Nandi, A. Prasad, Y. Xu, E. Poppleton, D. Williams, F. Zhang, H. Yan, P. Chiu*, N. Stephanopoulos*, and P. Šulc*

Coarse-Grained Simulations for the Characterization and Optimization of Hybrid Protein–DNA Nanostructures

ACS Nano 16, 14086- 14096 (2022).

216. L. Ma, Y. Liu, C. Han, A. Movsesyan, P. Li, H. Li, P. Tang, Y. Yuan, S. Jiang, W. Ni, H. Yan, A. Govorov, Z. Wang, X. Lan*

DNA-Assembled Chiral Satellite-Core Nanoparticle Superstructures: Two-State Chiral Interactions from Dynamic and Static Conformations

Nano Letters 22, 4784-4791 (2022).

215. K. Chen, F. Xu, Y. Hu, H. Yan*, L. Pan*

DNA Kirigami Driven by Polymerase-Triggered Strand Displacement

Small 18, 2201478 (2022).

214. X. Zhou, H. Liu, F. Djutanta, D. Satyabola, S. Jiang, X. Qi, L. Yu, S. Lin, R.F. Hariadi, Y. Liu, N.W. Woodbury*, H. Yan*

DNA-Templated Programmable Excitonic Wires for Micron-Scale Exciton Transport

Chem. 8, 2442-2459 (2022).

213. X. Zhou, S. Lin, H. Yan*

Interfacing DNA nanotechnology and biomimetic photonic complex: advances and prospects in energy and biomedicine

J. Nanobiotechnology 20: 257 (2022).

212. C. Simmons, T. MacCulloch, M. Krepl, M. Matthies, A. Buchberger, I. Crawford, J. Sponer, P. Sulc, N. Stephanopoulos* and H. Yan*

The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly

Nature Communications 13, article number 3112 (2022).

211. J. Bohlin', E. Poppleton', M. Matthies', J. Procyk', A. Mallya, H. Yan & P. Sulc*

Design and simulation of DNA, RNA, and hybrid protein-nucleic acid nanostructures with OxView

Nature Protocols 17, 1762-1788 (2022).

210. L. Liu, F. Hong, H. Liu, X. Zhou, S. Jiang, P. Sulc, J. Jiang*, H. Yan*

A localized DNA Finite State Machine with Temporal Resolution

Science Advances 8. DOI: 10.1126/sciadv.abm9530

(2022).

209. C. Zhang*, X. Ma, X. Zheng, Y. Ke, K. Chen, D. Liu, Z. Lu, J. Yang* and H. Yan*

Programmable Allosteric DNA Regulations for Molecular Networks and Nanomachines

Science Advances 5. DOI: 10.1126/sciadv.abl4589

(2022).

208. S. Dey, A. Dorey, L. Abraham, Y. Xing, I. Zhang, F. Zhang, S. Howorka*, H. Yan*

A Reversibly Gated Protein-Transporting Membrane Channel Made of DNA

Nature Communications 13, Article number: 2271 (2022)

2021

207. H. Liu, F. Hong, F. Smith, J. Goertz, T. Ouldridge, M. Stevens, H. Yan & P. Sulc*

Kinetics of RNA and RNA:DNA hybrid strand displacement

ACS Synth. Biol. 10, 3066-3073 (2021).

206. Y. Liu, L. Ma, S. Jiang, C. Han, P. Tang, H. Yang, X. Duan, N. Liu*, H. Yan* & X. Lan*

DNA Programmable Self-Assembly of Planar, Thin-Layered Chiral Nanoparticle Superstructures with Complex Two-Dimensional Patterns

ACS Nano 15, 16664-16672 (2021).

205. T. Yuan, Y. Shao, X. Zhou, Q. Liu, Z. Zhu, B. Zhou, Y. Dong, N. Stephanopoulos, S. Gui*, H. Yan*, D. Liu*

Highly Permeable DNA Supramolecular Hydrogel Promotes Neurogenesis and Functional Recovery after Completely Transected Spinal Cord Injury

Advanced Materials 33, 2102428, (2021).

204. Y. Zhang, Z. Qu, . Jiang, Y. Liu, R. Narayanan, D. Williams, X. Zuo, L. Wang, H. Yan, H. Liu* & C. Fan

Prescribing Silver Chirality with DNA Origami

J. Am. Chem. Soc 143, 8639-8646, (2021).

203. S. Jiang, N. Pal, F. Hong, N. E. Fahmi, H. Hu, M. Vrbanac, H. Yan*, N. G. Walter*, Y. Liu*

Regulating DNA Self-Assembly Dynamics with Controlled Nucleation

ACS Nano 15, 5384-5396, (2021).

202. S. Dey, C. Fan*, K. V. Gothelf*, J. Li*, C. Lin*, L. Liu, N. Liu*, M. A. D. Nijenhuis, B. Sacca*, F. C. Simmel*, H. Yan* & P. Zhan

DNA Origami

Nat. Rev. Methods Primers 1, 13, (2021).

2020

201. S. Jiang, Z. Ge, S. Mou, H. Yan*, C. Fan*

Designer DNA Nanostructures for Therapeutics

Chem 7, 1156-1179, (2020).

200. G. Yao', F. Zhang', F. Wang', T. Peng, H. Liu, E. Poppleton, P. Sulc, S. Jiang, L. Liu, C. Gong, X. Jing, X. Liu, L. Wang, Y. Liu, C. Fan*, H. Yan*

Meta-DNA Structures

Nature Chemistry 12, 1067-1075, (2020).

199. C.R. Simmons, T. MacCulloch, F. Zhang, Y. Liu, N. Stephanopoulos & H. Yan

A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High Resolution Structural Detail

Angew. Chem. Int. Ed. 59, 18619-18626, (2020).

198. S. Jiang, F. Zhang & H. Yan

Complex assemblies and crystals guided by DNA

Nat. Mater. 19, 694-700, (2020).

197. J. Georges, X. Qi, X. Liu, Y. Zhou, E. C. Woolf, A. Valeri, Z. Al-Atrache, E. Belykh, B. Feuerstein, M. Preul, A. C. Scheck, M. Reiser, T. Anderson, J. Gopez, D. Appelt, S. Yocom, J. Eschbacher, H. Yan, P. Nakaji

A Fluorescent Aptamer Provides Rapid and Specific Ex Vivo Diagnosis of Central Nervous System Lymphoma from Rodent Xenograft Biopsies

J. Neurosurg. in press, (2020).

196. J. Li', J. Dai', S. Jiang', M. Xie', T. Zhai, L. Guo, S. Cao, S. Xing, Z. Qu, Y. Zhao, F. Wang, Y. Yang, L. Liu, X. Zuo, L. Wang*, H. Yan*, C. Fan*

Encoding quantized fluorescence states with fractal DNA frameworks

Nat. Commun. 11, 2185, (2020).

195. X. Qi, X. Liu, L. Matiski, R. Rodriguez Del Villar, T. Yip, F. Zhang, S. Sokalingam, S. Jiang, L. Liu, H. Yan, Y. Chang

RNA Origami Nanostructures for Potent and Safe Anti-Cancer Immunotherapy

ACS Nano 14, 4727-4740, (2020).

194. F. Hong, D. Ma, K, Wu, L.A. Mina, R.C. Luiten, Y. Liu, H. Yan*, A.A. Green*

Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators

Cell 180, 1018-1032, (2020).

193. G. Yao, J. Li, Q. Li, X. Chen, X. Liu, F. Wang, Z. Qu, Z. Ge, R.P. Narayanan, D. Williams, H. Pei, X. Zuo, L. Wang, H. Yan, B.L. Feringa*, C. Fan*

Programming nanoparticle valence bonds with single-stranded DNA encoders

Nature Materials 19, 781-788, (2020).

2019

192. Z. Zhao, C. Wang, H. Yan,* Y. Liu*

Soft Robotics Programmed with Double Crosslinking DNA Hydrogels

Advanced Functional Materials 1905911, (2019).

191. C. Zhang*, Z. Wang, Y. Liu, J. Yang, X. Zhang, Y. Li, L. Pan, Y. Ke*, H. Yan*

Nicking- Assisted Reactant Recycle to Implement Entropy-Driven DNA Circuit

J. Am. Chem. Soc. 141, 17189-17197 (2019).

190. X. Jing, F. Zhang, P. Pan, X. Dai, J. Li, L. Wang, H. Yan, C. Fan

Solidifying framework nucleic acids with silica

Nature Protocols 14, 2416-2436, (2019).

189. Y. Zhou, X. Qi, Y. Liu, F. Zhang, H. Yan*

DNA Nanoscaffold-Assisted Selection of Femtomolar Bivalent Aptamers for Human α-Thrombin with Potent Anticoagulant Activity

ChemBioChem 20, 2494-2503, (2019).

188. X. Wang, A. Chandrasekaran, R. Arun, Z. Shen, Y. Ohayon, T. Wang, M. Kizer, R. Sha, C. Mao, H. Yan, X. Zhang, S. Liao, B. Ding, B. Chakraboty, N. Jonoska, D. Niu, H. Gu, J. Chao, X. Gao, Y. Li, T. Ciengshin, N. Seeman

Paranemic Crossover DNA: There and Back Again

Chemical Reviews, 119, 6273-6289, (2019).

187. X. Zhou, S. Mandal, S. Jiang, S. Lin, J. Yang, Y. Liu, D. Whitten, N. Woodbury*, H.Yan*

Efficient Long-range, Directional Energy Transfer through DNA-Templated Dye Aggregates

J. Am. Chem. Soc. 141, 8473-8481 (2019).

186. S. Mandal, X. Zhou, S. Lin, H. Yan*, N. Woodbury*

Directional Energy Transfer through DNA-Templated J-aggregates

Bioconjugate Chemistry 30, 1870-1879 (2019).

185. Z. Ge, Z. Su, C. R. Simmons, J. Li, S. Jiang, W. Li, Y. Yang, Y. Liu*, W. Chiu, C. Fan*, H. Yan*

Rodox Engineering of Cytochrome c using DNA Nanostructure-Based Charge Encapsulation and Spatial Control

ACS Applied Materials & Interfaces 11, 13874-13880 (2019).

184. Z. Ge, J. Fu, M. Liu, S. Jiang, A. Andreoni, X. Zuo, Y. Liu, H. Yan*, C. Fan*

Constructing Submonolayer DNA Origami Scaffold on Gold Electrode for Wiring of Redox Enzymatic Cascade Pathways

ACS Applied Materials & Interfaces 11, 13881-13887 (2019).

183. L. Xin, M. Lu, S. Both, M. Pfeifer, M. Urban, C. Zhou, H. Yan, T. Weiss, N. Liu, K. Lindfors

Watching a Single Fluorofphore Molecule Walk into a Plasmonic Hotspot

ACS Photonics 6, 985-993 (2019).

182. Y. Xu, S. Jiang, C. Simmons, R. Narayanan, F. Zhang, A. Aziz, H. Yan, N. Stephanopoulos*

Tunable Nanoscale Cages from Self-Assembling DNA and Protein Building Blocks

ACS Nano 13, 3545–3554, (2019).

181. H. Jun, F. Zhang, T. Shepherd, S. Ratanalert, X. Qi, H. Yan, M. Bathe

Autonomously designed free-form 2D DNA origami

Science Advances, 5, eaav0655 (2019).

2018

180. D. Jiang, Z. Ge, H. Im, C. England, D. Ni, J. Hu, L. Zhang, C. Kutyreff, Y. Yan, Y. Liu, S. Cho, J. Engle, J. Shi, P. Huang, C. Fan*, H. Yan*, W. Cai*

DNA-origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury

Nature Biomedical Engineering 2, 865-877 (2018).

179. X. Qi, F. Zhang*, Z. Su', S. Jiang, D. Han, B. Ding, Y. Liu, W. Chiu, P. Yin, H. Yan*

Programing Molecular Topologies from Single-stranded Nucleic Acids

Nature Communications 9, 4579 (2018).

178. F. Hong, S. Jiang, X. Lan, R. Narayanan, P. Sulc, F. Zhang*, Y. Liu*, H. Yan*

Layered- Crossover Tiles with Precisely Tunable Angles for 2D and 3D DNA Crystal Engineering

J. Am. Chem. Soc. 140, 14670-14676 (2018).

177. X. Lan, T. Liu, Z. Wang, A. Govorov, H. Yan, Y. Liu

DNA-Guided Plasmonic Helix with Switchable Chirality

J. Am. Chem. Soc. 140, 11763-11770 (2018).

176. F. Zhang, C. Simmons, J. Gates, Y. Liu, H. Yan*

Self-Assembly of a 3D DNA Crystal Structure with Rationally Designed Six-Fold Symmetry

Angew Chem Int Ed. 57, 12504-12507 (2018).

175. X. Liu, F. Zhang, X. Ling, M. Pan, P. Liu, W. Li, B. Zhu, J. Li, H. Chen, L. Wang, J. Lin, Y. Liu, D. Zhao, H. Yan*, C. Fan*

Complex Silica Composite Nanomaterials Templated with DNA Origami

Nature, 559, 593-598, (2018).

174. Z. Ge, Z. Su, C. R. Simmons, J. Li, S. Jiang, W. Li, Y. Yang, Y. Liu, W. Chiu, C. Fan, H. Yan*

Redox Engineering of Cytochrome c using DNA Nanostructure-Based Charged Encapsulation and Spatial Control

ACS Appl. Mater. Interfaces. DOI:10.1021/acsami.8b07101

(2018).

173. Li, A. Johnson-Buck, Y. Yang, W. Shih, H. Yan, N. Walter

Exploring the speed limit of toehold exchange with a cartwheeling DNA acrobat

Nature Nanotechnology 13, 723-729, (2018).

172. S. Li, Q. Jiang, C. Song, Y. Tian, J. Wang, S. Liu, Y. Zhang, Y. Zou, G. Anderson, J. Han, Y. Chang, Y. Liu, H. Yan*, G. Nie*, B. Ding, Y. Zhao*

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

Nature Biotechnology, 36, 258-264 (2018).

171. E. Boulais, N.Sawaya, R. Veneziano, A. Andreoni, S. Lin, N. Woodbury, H. Yan*, M. Bathe*

Programmed coherent coupling in a DNA-based excitonic circuit

Nature Materials, 17, 159-166 (2018).

2017

170. D. Han, X. Qi, C. Myhrvold, B. Wang, M. Dai, S. Jiang, M. Bates, Y. Liu, B. An*, F. Zhang*, H. Yan*, P. Yin*

Single-stranded DNA and RNA Origami

Science, 358, 1402 (2017).

169. F. Zhang, H. Yan*

DNA Self-assembly scaled up

Nature, 552, 34 (2017).

168. Y.R. Yang; J. Fu, S. Wootten, X. Qi, M. Liu, H. Yan, Y. Liu*

2D Enzyme Cascade Network with Efficient Substrate Channeling by Swinging Arms

ChemBioChem. DOI: 10.1002/cbic.201700613

(2017).

167. J. Li, A. A. Green, H. Yan, C. Fan

Engineering nucleic acid structures for programmable molecular circuitry and intracellular biocomputation

Nature Chemistry. DOI:10.1038/nchem.20405

(2017).

166. C. Simmons, F. Zhang, T. MacCulloch, N. Fahmi, N. Stephanopoulos, Y. Liu, N. Seeman, H. Yan

Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals

J. Am. Chem. Soc. 139, 11254-11260 (2017).

165. D. Mieritz, X. Li, A. Volosin, M. Liu, H. Yan, N. Walter, D. Seo

Tracking Single DNA Nanodevices in Herarchically Meso-Macroporous Antimony-Doped Tin Oxide Demonstrates Finite Confinement

Langmuir 33, 6410-6418 (2017).

164. H. Zhang, A. Carey, K. Jeon, M. Liu, T. Murell, J. Locsin, S. Lin, H. Yan, N. Woodbury, D. Seo

A Highly Stable and Scalable Photosynthetic Reaction Center-Graphene Hybrid Electrode System for Biomimetic Solar Energy Transduction

J. Mater. Chem. A. 5, 6038–6041, (2017).

163. A. Carey, H. Zhang, M. Liu, D. Sharaf, N. Akram, H. Yan, S. Lin, N. Woodbury*, D. Seo*

Enhancing Photocurrent Generation in Photosynthetic Reaction Center-based Photoelectrochemical Cells with Biomimetic DNA Antenna

ChemSusChem 10, 4457- 4460 (2017).

162. S. Jiang, F. Hong, H. Hu, H. Yan*, Y. Liu*

Understanding the Elementary Steps in DNA Tile-based Self-assembly

ACS Nano. 11, 9370-9381 (2017).

161. H. Fan, F. Zhang, Y. Liu*, H. Yan*

DNA Origami, Scaffolds for Creating Higher Order Structures

Chemical Reviews, Chemical Review, in press (2017).

160. F. Zhang, F. Hong, H. Yan*

DNA Origami Tiles: Nanoscale Mazes

Nature. Nanotechnology. 12, 189-190 (2017).

159. Y. Dong, Y. Yang, Y. Zhang, D. Wang, X. Wei, S. Banerjee, Y. Liu, Z. Yang, H. Yan*, D. Liu*

Cuboid Vesicles Formed by Frame-guided Assembly on DNA Origami Scaffolds

Angew Chem Int Ed. 156, 1586-1589, (2017).

158. A. Andreoni, S. Lin, H. Liu, R. E. Blankenship, H. Yan, N. Woodbury

Orange Carotenoid Protein as a Control Element in an Antenna System based on a DNA Nanostructure

Nano Letters, 17, 1174-1180 (2017).

2016

157. F. Hong, S. Jiang, T. Wang, Y. Liu*, H. Yan*

3D Framework DNA origami with Layered Crossovers

Angew Chem Int Ed. 128, 13024–13027, (2016).

156. A. Carey, H. Zhang, D. Mieritz, A. Volosin, A. Gardiner, R. Cogdell, H. Yan, D. Seo, S. Lin, N. Woodbury*

Photocurrent generation by photosynthetic purple bacterial reaction centers interfaced with a porous antimony-doped tin oxide (ATO) electrode

ACS Appl. Matter. Interfaces 8, 25104–25110, (2016).

155. J. Fu*, Y. Yang, S. Dhakal, Z. Zhao, M. Liu, T. Zhang, N. Walter, H. Yan

Assembly of Multi-Enzyme Complexes on DNA Nanostructures

Nature Protocols 11, 2243–2273, (2016).

154. C. Simmons, F. Zhang, J. Birktoft, X. Qi, D. Han, Y. Liu, R. Sha, H. Abdallah, C. Hernandez, Y. Ohayon, N. Seeman*, H. Yan*

Construction and Structure Determination of a Three-dimensional DNA Crystal

J. Am. Chem. Soc. 138, 10047–10054, (2016).

153. R. Veneziano, S. Ratanalert, K. Zhang, F. Zhang, H. Yan, W. Chiu, M. Bathe*

Designer nanoscale DNA assemblies programmed from the top down

Science 10.1126/science.aaf4388 (2016).

152. F. Zhang*, S. Jiang, W. Li, A. Hunt, Y. Liu*, H. Yan*

Self-assembly of Complex DNA Tessellations using low symmetry multi-arm DNA tiles

Angew Chem Int Ed. 55, 8860–8863 (2016).

151. G. Ke, M. Liu, S. Jiang, X. Qi, Y. R. Yang, S. Wootten, F. Zhang, Z. Zhu, Y. Liu*, C. J. Yang*, H. Yan*

Directional Regulation of Enzyme Pathways via the Control of Substrate Channeling on a DNA Origami Scaffold

Angew Chem Int Ed., 55, 7483-7486 (2016).

150. M. Liu; J. Fu; X. Qi; S. Wootten; N. Woodbury; Y. Liu*; H. Yan*

A three-enzyme pathway with an optimized geometric arrangement to facilitate substrate transfer

ChemBioChem, 17, 1097-1101 (2016).

(Featured as inside cover of the Journal)

149. S. Dokal, M. Adendorff, M. Liu, H. Yan*, M. Bathe*, N. Walter*

Rational design of DNA-actuated enzyme nanoreactors guided by single molecule analysis

Nano Scale 8, 3125-3137 (2016).

148. W. Li, F. Zhang, H. Yan*, Y. Liu*

DNA Based Arithmetic Function: Half Adder Based on DNA Strand Displacement

Nanoscale 8, 3775-3784 (2016).

147. Z. Zhao, J. Fu. S. Dokal, A. Johnson-Buck, M. Liu, Y. Liu, N. Woodbury, N. Walter, H. Yan*

Nancaged Enzymes with Enhanced Catalytic Activity and Increased Stability Against Protease Digestion

Nature Communications 7, 10619 (2016).

146. C. Zhang, J. Yang, S. Jiang, Y. Liu*, H. Yan*

DNAzyme-based Logic Gate-mediated DNA Self-assembly

Nano Letters, 16, 736–741, (2016)

2015

145. F. Zhang, S. Jiang, S. Wu, Y. Li, C. Mao, Y. Liu*, H. Yan*

Complex wireframe DNA origami nanostructures with multi-arm junction vertices

Nature Nanotechnology, 10, 779-784 (2015).

(Featured as Front Cover of the Journal)

144. Y. Yang, Y. Liu, H. Yan*

DNA nanostructures as programmable biomolecular scaffolds

Bioconjugate Chemistry

143. J. F. Georges, X. Liu, J. Eschbacher, J. Nichols, M. A. Mooney, A. Joy, R. F. Spetzler, B. G. Feuerstein, M. C. Preu, T. Anderson, H. Yan, P. Nakaji*

Use of a Conformational Switching Aptamer for Rapid and Specific Ex Vivo Identification of Central Nervous System Lymphoma in a Xenograft Model

PloS one, 10(4), e0123607 (2015).

2014

142. K. Pan, D. N. Kim, F. Zhang, M. Adendorff, H. Yan, M. Bathe*

Lattice-free prediction of three-dimensional structure of programmed DNA assemblies

Nature Communications, 5, 5578 (2014).

141. P. Dutta, S. Levenberg, A. Loskutov, D. Jun, R. Saer, J. Beatty, S. Lin, Y. Liu, N. Woodbury*, H. Yan*

A DNA-Directed Light-Harvesting/Reaction Center System

J. Am. Chem. Soc., 136, 16618-16625 (2014).

140. A. Samanta, Y. Zhou, S. Zou, H. Yan, Y. Liu*

Fluorescence Quenching of Quantum Dots by Gold Nanoparticles: a Potential Long Range Spectroscopic Ruler

Nano Letters, 14, 5052–5057 (2014).

139. F. Zhang, J. Nangreave, Y. Liu, H. Yan*

Structural DNA Nanotechnology: State of the Art and Future Perspective

J. Am. Chem. Soc., 136, 11198–11211 (2014).

138. D. Wang, S. Capehart, S. Pal, M. Liu, L. Zhang, J. Schuck, Y. Liu, H. Yan, M. Francis, J. De Yoreo*

Hierarchical Assembly of Plasmonic Nanostructures using Virus Capsid Scaffolds on DNA Origami Templates

ACS Nano, 8, 7896–7904 (2014).

137. J. Flory, C. Simmons, S. Lin, T. Jonhson, A. Andreoni, J. Zook, G. Chirlanda, Y. Liu, H. Yan, and P. Fromme

Low Temperature Assembly of Functional 3D DNA-PNA-Protein Complexes

J. Am. Chem. Soc., 136, 8283-8295 (2014).

136. A. Johnson-Buck, S. Jiang, H. Yan, and N. G. Walter

DNA-Cholesterol Barges as Programmable Membrane-Exploring Agents

ACS Nano, 8, 5641-5649 (2014).

135. L. Liang, J. Li, Q. Li, Q. Huang, J. Shi, H. Yan, and C. Fan

Single-particle Tracking and Modulation of Cell Entry Pathways of a Tetrahedral DNA Nanostructure in Live Cells

Angew Chem Int Ed., 53, 7745-7750 (2014).

134. J. Fu, Y. R. Yang, A. Johnson-Buck, Y. Liu, N. G. Walter, N. W. Woodbury, and H. Yan

Multi-enzyme Complexes on DNA Scaffolds Capable of Substrate Channeling with an Artificial Swinging Arm

Nature Nanotechnology, 9, 531-536 (2014).

133. S. Jiang, H. Yan, and Y. Liu

Kinetics of DNA Tile Dimerization

ACS Nano., 8, 5826-5832 (2014).

132. W. Li, Y. Yang, S. Jiang, H. Yan, and Y. Liu

Controlled Nucleation and Growth of DNA Tile Arrays within Prescribed DNA Origami Frames and Their Dynamics

J. Am. Chem. Soc., 136, 3724-3727 (2014).

131. P. Dutta, S. Lin, A. Loskutov, S. Levenberg, D. Jun, R. Saer, J. Beatty, Y. Liu, H. Yan, and N. Woodbury

Reengineering the Optical Absorption Cross-section of Photosynthetic Reaction Centers

J. Am. Chem. Soc., 136, 4599-4604 (2014).

2013

130. D. Han, S. Jiang, A. Samanta, Y. Liu, and H. Yan

Unidirectional Scaffold-Strand Arrangement in DNA Origami

Angew Chem Int Ed., 52, 9031-9034 (2013).

129. Q. Mei, R. H. Johnson, X. Wei, F. Su, Y. Liu, L. Kelbauskas, S. Lindsay, D. R. Meldrum, and H. Yan

On-chip Isotachophoresis Separation of Functional DNA Origami Capture Nanoarrays from Cell Lysate

Nano Research, 6, 712-719 (2013).

128. M. Liu, J. Fu, C. Hejesen, Y. Yang, N. W. Woodbury, K. Gothelf, Y. Liu, and H. Yan

A DNA Tweezer-Actuated Enzyme Nanoreactor

Nature Comm., 4:2127 (2013).

127. S. Pal, P. Dutta, H. Wang, Z. Deng, S. Zou, H. Yan, and Y. Liu

Quantum Efficiency Modification of Organic Fluorophores Using Gold Nanoparticles on DNA Origami Scaffolds

J. Phys. Chem. C, 117, 12735–12744, (2013).

126. W. Li, Y. Yang, H. Yan, and Y. Liu

3-Input Majority Logic Gate and Multiple Input Logic Circuit Based on DNA Strand Displacement

Nano Letters, 13, 2980–2988, (2013).

125. A. Johnson-Buck, J. Nangreave, S. Jiang, H. Yan, and N. Walter

Multifactorial Modulation of Binding and Dissociation Kinetics on Two-Dimensional DNA Nanostructures

Nano Letters, 13, 2754–2759, (2013).

124. F. Zhang, Y. Liu, and H. Yan

Complex Archimedean Tiling Self-assembled from DNA Nanostructures

J. Am. Chem. Soc., 135, 7458–7461, (2013).

123. X. Wei, J. Nangreave, S. Jiang, H. Yan, and Y. Liu

Mapping the Thermal Behavior of DNA Origami Nanostructures

J. Am. Chem. Soc., 135, 6165–6176, (2013).

122. J. Flory, S. Shinde, S. Lin, Y. Liu, H. Yan, G. Ghirlanda, and P. Fromme

PNA-peptide Assembly in a 3D DNA Nanocage at Room Temperature

J. Am. Chem. Soc., 135, 6985–6993, (2013).

121. Y. Yang, Z. Zhao, F. Zhang, J. Nangreave, Y. Liu, and H. Yan

Self-assembly of DNA Rings from Scaffold Free DNA Tiles

Nano Letters, 13, 1862–1866, (2013).

120. O. Schulz, Z. Zhao, A. Ward, M. Koenig, F. Koberling, Y. Liu, J. Enderlein, H. Yan and R. Ros

Tip Induced Fluorescence Quenching for Nanometer Optical and Topographical Resolution

Optical Nanoscopy, 2:1, (2013).

119. Z. Deng, S. Pal, A. Samanta, H. Yan, and Y. Liu

DNA Functionalization of Colloidal II-VI Semiconductor Nanowires

Chemical Sciences, 3, 2234–2240, (2013).

118. X. Liu, Y. Liu, and H. Yan

Functionalized DNA Nanostructures for Nanomedicine, Israel Journal of Chemistry, Special Issue on Supramolecular Chemistry for Materials and Medicine,

(eds: Steven C. Zimmerman, Alanna Schepartz) Invited review, 53, 555-566, (2013).

117. A. Johnson-Buck, J. Nangreave, D. Kim, M. Bathe, H. Yan, and N. Walter

Super-Resolution Fingerprinting Detects Chemical Reactions and Idiosyncrasies of Single DNA Pegboards

Nano Letters, 13, 728-733 (2013).

116. D. Han, S. Pal, Y. Yang, S. Jiang, J. Nangreave, Y. Liu, and H. Yan

DNA Gridiron Nanostructures Based on Four-Arm Junctions

Science, 339, 1412-1415 (2013).

115. Z. Zhao, Y. Liu, and H. Yan

DNA Origami Templated Self-assembly of Discrete Length Single Wall Carbon Nanotubes

Org. Biomol. Chem., 11, 596-598 (2013).

2012

114. Z. Deng, A. Sanmanta, J. Nangreave, H. Yan, and Y. Liu

Robust DNA Functionalized Core/Shell Quantum Dots with Fluorescent Emission Spanning from UV-Vis to Near IR and Compatible with DNA Directed Self-Assembly

J. Am. Chem. Soc., 134, 17424-17427 (2012).

113. Y. Yang, D. Han, J. Nangreave, Y. Liu, and H. Yan

DNA Origami with Double-Stranded DNA As a Unified Scaffold

ACS Nano, 6, 8209-8215 (2012).

112. N. Lu, H. Pei, Z. Ge, C. R. Simmons, H. Yan, and C. Fan

Charge Transport within A Three-Dimensional DNA nanostructure Framework

J. Am. Chem. Soc., 134, 13148-13151 (2012).

111. Q. Jiang, C. Song, J. Nangreave, X. Liu, L. Lin, D. Qiu, Z. Wang, G. Zou, X. Liang, H. Yan, and B. Ding

DNA Origami as a Carrier for Circumvention of Drug Resistance

J. Am. Chem. Soc., 134, 13396-13403 (2012).

110. X. Liu, Y. Xu, T. Yu, C. Craig, Y. Liu, H. Yan, and Y. Chang

A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines

Nano Letters, 12, 4254-4259 (2012).

109. J. Fu, M. Liu, Y. Liu, and H. Yan

Spatially-Interactive Biomolecular Networks Organized by Nucleic Acid Nanostructures

Acc. Chem. Res. 45, 1215-1226 (2012).

108. F. Zhang, J. Nangreave, Y. Liu, and H. Yan

Reconfigurable DNA Origami to Generate Quasi-Fractal Patterns

Nano Letters, 12, 3290–3295 (2012).

107. A. V. Pinheiro, J. Nangreave, S, Jiang, H. Yan, and Y. Liu

Steric Crowding and the Kinetics of DNA Hybridization within a DNA Nanostructure System

ACS Nano, 6, 5521–5530 (2012).

106. J. Fu and H. Yan

Controlled Drug Release by a Nanorobot

Nature Biotechnol. 30, 407–408 (2012).

105. J. Fu, M. Liu, Y. Liu, N. W. Woodbury, and H. Yan

Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures

J. Am. Chem. Soc. 134, 5516–5519 (2012).

104. Z. Li, L. Wang, H. Yan, and Y. Liu

Effect of DNA Hairpin Loops on the Twist of Planar DNA Origami Tiles

Langmuir, 28, 1959–1965 (2012).

2011

103. A. Pinheiro, D. Han, W. M. Shih, and H. Yan

Challenges and Opportunities for Structural DNA Nanotechnology

Nature Nanotechnology. 6, 763-772, 2011.

102. S. Pal, Z. Deng, Y. Liu, and H. Yan

DNA Origami Directed Self-assembly of Anisotropic Plasmonic Nanostructures

J. Am. Chem. Soc. 133, 17606-17609, 2011.

101. P. Dutta, R. Varghese, S. Lin, H. Yan, and Y. Liu

DNA Directed Artificial Light Harvesting Systems

J. Am. Chem. Soc. 133, 11985-11993, 2011.

100. C. R. Simmons , D.Schmitt , X. Wei , D. Han , A. M. Volosin , D. M Ladd , D. Seo, Y. Liu, and H. Yan

Size-selective Incorporation of DNA Nanocages into Nanoporous Antimony-doped Tin Oxide Materials

ACS Nano, 5, 6060-6068, 2011.

99. Z. Zhao, Y. Liu, and H. Yan

Organizing DNA Origami Tiles into Larger Structures Using Pre-formed Scaffold Frames

Nano Letters, 11, 2997-3002, 2011.

98. T. Torring, N. V. Voigt, J. Nangreave, H. Yan, and K. Gothelf

DNA Origami: A Quantum Leap for Self-assembly of Complex Structures

Chem. Soc. Rev, 40, 5636-5646, 2011.

97. X. Liu, H. Yan, Y. Liu, and Y. Chang

Targeted Cell-Cell Interactions by DNA Nanoscaffold-Templated Multivalent Bi-specific Aptamers

Small, 7, 1673-1682, 2011.

96. D. Han*, S. Pal, J. Nangreave, Z. Deng, Y. Liu, and H. Yan

DNA Origami with Complex Curvatures in Three-dimensional Space

Science, 332, 342-346 2011.

(Featured as cover story of the April 15 issue of Science) This work was highlighted by National Science Foundation news release with video story (http://www.nsf.gov/news/news_summ.jsp?cntn_id=119245&org=NSF&from=news)

95. S.Pal, R. Varghese, H. Yan, and Y. Liu

Site Specific Synthesis and in-situ Immobilization of Fluorescent Silver Nanoclusters on DNA Nanoscaffolds Using Tollens Reaction

Angew Chem Int Ed, 50, 4176-4179, 2011.

94. Z. Deng, L. Tong, S. Lin, M. Flores, J. Cheng, H. Yan, and Y. Liu

High Quality Manganese-Doped Zinc Sulfide Quantum Rods with Tunable Dual-Color and Multi-Photon Emissions

J. Am. Chem. Soc, 133, 5389-5396, 2011.

93. J. Nangreave, H. Yan, and Y. Liu

DNA Nanostructures as Models for Evaluating the Role of Enthalpy and Entropy in Polyvalent Binding

J. Am. Chem. Soc, 133, 4490-4497, 2011.

92. Q. Mei, X. Wei, F. Su, Y. Liu, C. Youngbull, R. Johnson, S. Lindsay, H. Yan, and D. Meldrum

Stability of DNA Origami Nanoarrays in Cell Lysate

Nano Letters, 11, 1477-1482, 2011.

91. Z. Zhao, Y. Liu, and H. Yan

Encapsulation of Gold Nanoparticles in a DNA Origami Cage

Angew Chem Int Ed, 50, 2041-2044, 2011.

2010

90. B. Ding, H. Wu, W. Xu, Z. Zhao, Y. Liu, H. Yu, and H. Yan

Interconnecting Gold islands with DNA Origami Nanotubes

Nano Letters, 10, 5065-5069, 2010.

89. D. Han, S. Pal, Y. Liu, and H. Yan

Folding and Cutting DNA into Reconfigurable Topological Nanostructures

Nature Nanotechnology, 5, 712–717, 2010.

88. Z. Li, M. Liu, L. Wang, J. Nangreave, H. Yan, and Y. Liu

Molecular Behavior of DNA Origami in Higher Order Self-assembly

J. Am. Chem. Soc, 138, 13545–13552, 2010.

87. Z. Deng, H. Yan, and Y. Liu

Controlled Colloidal Growth of Ultra-Thin Single-Crystal ZnS Nanowires with Magic-Size Diameter

Angew. Chem. Int. Ed. 49, 8695-8698, 2010.

86. H. Pei, N. Lu, Y. Wen, S. Song, Y. Liu, H. Yan, and C. Fan

A DNA Nanostructure-based Biomolecular Probe Carrier Platform for Electrochemical Biosensing

Advanced Materials, 22, 4754–4758, 2010.

85. J. Nangreave, D. Han, Y. Liu, and H. Yan

DNA Origami: A History and Current Perspective

Curr Opin Chem Biol, 14, 608–615, 2010.

84. N. Stephanopoulos; M. Liu; G. Tong; Z. Li; Y. Liu; H. Yan; and M. Francis

Immobilization and One-Dimensional Arrangement of Virus Capsids With Nanoscale Precision Using DNA Origami

Nano Lett. 10, 2714-2720, 2010.

83. K. Lund, A. J. Manzo, N. Dabby, N. Michelotti, A. Johnson-Buck, J. Nangreave, Steven Taylor, R. Pei, M. N. Stojanovic, N. G. Walter, E. Winfree, and H. Yan

Molecular Robots Guided by Prescriptive Landscapes

Nature 465, 206-210 (2010).

82. Z. Deng, O. Schulz, S. Lin, B. Ding, X. Liu, X. Wei, R. Ros, H. Yan, and Y. Liu

Aqueous Synthesis of Zinc-Blende CdTe/CdS Magic-Core/Thick-Shell Tetrahedral Shaped Nanocrystals with Emission Tunable to Near-Infrared

J. Am. Chem. Soc. 132, 5592-5593 (2010).

81. S. Pal, Z. Deng, B. Ding, H. Yan, and Y. Liu

DNA Origami Directed Self-assembly of Discrete Silver Nanoparticle Architectures

Angew Chem Int Ed 49, 2700-2704 (2010).

80. . Ding, Z. Deng, H. Yan, S. Cabrini, R. Zukerman, and J. Borker

Gold Nanoparticles Self-similar Chain Structure Organized by DNA Origami

J. Am. Chem. Soc. 132, 3248-3249, (2010).

79. R. Chhabra, J. Sharma, Y. Liu, S. Rinker, and H. Yan

DNA Self-assembly for Nanomedicine

Advanced Drug Delivery Reviews 62, 617-625 (2010).

78. Z. Zhao, H. Yan, and Y. Liu

A Route to Scale up DNA Origami using DNA Tiles as Folding Staples

Angew Chem Int Ed 49, 1414-1417 (2010).

77. S. Williams, K. Lund, C. Lin, P. Wonka, S. Lindsay, and H. Yan

Tiamat: A Three Dimensional Editing Tool for Complex DNA Structures

DNA Computing: Lecture Notes in Computer Science, 5347, 90-101 (2010).

2009

76. Z. Deng, H. Yan, and Y. Liu

Band Gap Engineering of Quaternary Alloyed ZnCdSSe Quantum Dots via a Facile Phosphine-Free Colloidal Method

J. Am. Chem. Soc. 131, 17744 (2009).

75. R. Chhabra, J. Sharma, H. Wang, S. Lin, H. Yan, S. Zou, S. Lindsay, and Y. Liu

Distance-dependent Interactions between Gold Nanoparticles and Fluorescent Molecules with DNA as Tunable Spacers

Nanotechnology, 20, 485201 (2009).

74. Y. Ke, S. Douglas, M. Liu, J. Sharma, A. Cheng, A. Leung, Y. Liu, W. Shih, and H. Yan

Multilayer DNA Origami Packed On a Square Lattice

J. Am. Chem. Soc. 131, 15903-15908 (2009).

73. L. A. Stearns, R. Chhabra, J. Sharma, Y. Liu, W. T. Petuskey, H. Yan, and J. C

Chaput, Template-Directed Nucleation and Growth of Inorganic Nanoparticles on DNA Scaffolds

Angew. Chem. Int. Ed. 45, 8494-8496 (2009).

72. Z. Li, B. Wei, J. Nangreave, C. Lin, Y. Liu, Y. Mi, and H. Yan

A Replicable Tetrahedral Nanostructure Self-assembled from a Single DNA Strand

J. Am. Chem. Soc. 131, 13093-13098 (2009).

71. S. Pal, J. Sharma, H. Yan, and Y. Liu

Stable Silver Nanoparticle-DNA Conjugates for Directed Self-assembly of Core-Satelite Silver Nanoclusters

Chemical Communication. 6059-6061 (2009).

70. Y. Liu and H. Yan

Designer Curvature

Science 325, 685-686 (2009).

69. Y. Liu and H. Yan

Coordinating Corners

Nature Chemistry 1, 339-340 (2009).

68. J. Nangreave, H. Yan, and Y. Liu

Studies of Thermal Stability of Multivalent DNA Hybridization in a Nanostructured System

Biophys. J. 97, 563-571 (2009).

67. A. E. Gerdon, S.-S. Oh, W. Hsieh, Y. Ke, H. Yan, and H. T. Soh

Controlled Delivery of DNA Origami on Patterned Surface

Small 5, 1942-1946 (2009).

66. C. Andersen, M. Knudsen, R. Chhabra, Y. Liu, H. Yan, and K. Gothelf

Distance Dependent Interhelical Couplings of Organic Rods Incorporated in DNA 4-Helix Bundles

Bioconjugation Chemistry 20, 1538-1546 (2009).

65. Y. Ke, J. Sharma, M. Liu, K. Jahn, Y. Liu, and H. Yan

Scaffolded DNA Origami of a DNA Tetrahedron Molecular Container

Nano. Lett. 9, 2445-2447 (2009).

64. C. Lin and H. Yan

Engaging Enzyme Cascades on DNA Scaffolds

Nature Nanotechnology 4, 211-212 (2009).

63. C. Lin, Y. Liu, and H. Yan

Designer DNA Nanoarchitectures

Biochemistry, 48, 1663-1674 (2009).

62. J. Sharma, R. Chhabra, A. Cheng, J. Brownell, Y. Liu, and H. Yan

Control of Self-Assembly of DNA Tubules Through Integration of Gold Nanoparticles

Science, 323, 112-116 (2009).

61. C. Lin, Y. Ke, Z. Li, J. Wang, Y. Liu, and H. Yan

Mirror Image DNA Nanostructures for Chiral Supramolecular Assemblies

Nano Letters. 9, 433-436 (2009).

2008

60. C. Lin, S. Rinker, X. Wang, Y. Liu, N. C. Seeman, and H. Yan

In-vivo Cloning of DNA Nanostructures

Proc. Natl. Acad. Sci. 105, 17626-17635 (2008).

59. Z. Li, Y. Ke, C. Lin, H. Yan, and Y. Liu

Subtractive Assembly of DNA Nanoarchitectures Driven by Fuel Strand Displacement

Chem. Comm 4318-4320 (2008).

58. C. Lin, J. Nangreave, Z. Li, H. Yan, and Y. Liu

Signal Amplification on a DNA Tile Based Biosensor with Enhanced Sensitivity

Nanomedicine 3, 521-528 (2008).

57. Y. Xu, Q. Wang, P. He, Q. Dong, F. Liu, Y. Liu, L. Lin, H. Yan, and X. Zhao

Cell Nucleus Penetration by Quantum Dots Induced by Nuclear Staining Organic Fluorophore and UV-Irradiation

Advanced Materials 20, 3468-3473 (2008).

56. J. Sharma, R. Chhabra, C. S. Anderson, K. V. Gothelf, H. Yan, and Y. Liu

Toward Reliable Gold Nanoparticle Patterning on Self-assembled DNA Nanoscaffold

J. Am. Chem. Soc 130, 7820-2821 (2008).

55. C. S. Anderson, H. Yan, and K. V. Gothelf

Bridging One Helical Turn in dsDNA by Templated Dimerization of Molecular Rods

Angew Chem Int Ed 47, 5569-5572 (2008).

54. J. Sharma, Y. Ke, C. Lin, R. Chhabra, Q. Wang, J. Nangreave, Y. Liu, and H. Yan

DNA Tile Directed Self-assembly of Quantum Dots into Two-dimensional Nanopatterns

Angew Chem Int Ed 47, 5157-5159 (2008).

53. S. Rinker, Y. Ke, Y. Liu, and H. Yan

Self-assembled DNA Nanostructures for distance dependent multivalent ligand-protein binding

Nature Nanotechnology 3, 418-422 (2008).

52. Y. Ke, S. Lindsay, Y. Chang, Y. Liu, and H. Yan

Self-assembled Water-soluble Nucleic Acid Probe Tiles for Label Free RNA Detection

Science 319, 180-183 (2008).

This paper has been highlighted by Reuters and many other news agencies and was commented by high profile journals such as Nature Biotechnology (http://www.nature.com/nbt/journal/v26/n3/full/nbt0308-299.html), Nature Methods (http://www.nature.com/nmeth/journal/v5/n3/full/nmeth0308-222.html).

51. J. Sharma, R. Chhabra, H. Yan, and Y. Liu

A Facile In situ Generation of Dithiocarbamate Ligands for Stable Gold Nanoparticle-Oligonucleotide Conjugates

Chemical Communication 18, 2140-2142 (2008).

50. Q. Wang, Y. Liu, Y. Ke, and H. Yan

Quantum Dots Bioconjugation During Core-Shell Synthesis

Angew Chem Int Ed. 47, 316-319 (2008).

2007

49. C. Lin, X. Wang, Y. Liu, N. C. Seeman, and H. Yan

Rolling Circle Enzymatic Replication of a Complex Multi-crossover DNA Nanostructure

J. Am. Chem. Soc. 129, 14475-14481 (2007).

48. R. Chhabra, J. Sharma, Y. Ke, Y. Liu, S. Rinker, S. Lindsay, and H. Yan

Spatially Addressable Multi-protein Nanoarrays Templated by Aptamer Tagged DNA Nanoarchitectures

J. Am. Chem. Soc. 129, 10304-10305 (2007).

This paper was highlighted by the editor of Nature Nanotechnology as “Research Highlight”: http://www.nature.com/nnano/reshigh/2007/0807/full/nnano.2007.287.html

47. Q. Wang, Y. Liu, and H. Yan

Layer-by-layer Growth of Superparamagnetic and Fluorecently Barcoded Nanospheres

Nanotechnology 18, 40, 405026 (2007).

46. C. Lin, Y. Liu, M. Mertig, J. Gu, and H. Yan

Functional DNA Nanotube Arrays: Bottom-up Meets Top-down

Angew. Chem. Int. Ed. 46, 6089-6092 (2007).

This paper was chosen by the editors as “Hot Paper”: http://www3.interscience.wiley.com/cgi-bin/jabout/26737/2002_hotpaper.html

45. Q. Wang, Y. Liu, and H. Yan

Mechanism of a Self-templating Synthesis of Monodispersed Hollow Silica Nanospheres with Tunable Size and Shell Thickness

Chemical Communication 2339-2341 (2007)

44. Q. Wang, Y. Xu, X. Zhao, Y. Chang, Y. Liu, L. Jiang, J. Sharma, D.-K. Seo, and H. Yan

A Facile One-step In situ Functionalization of Quantum Dots with Preserved Photoluminescence for Bioconjugation

J. Am. Chem. Soc. 129, 6380-6381, (2007).

43. B. Williams, K. Lund, Y. Liu, H. Yan, and J. Chaput

Self-assembled Peptide Nanoarrays: An Approach to Studying Protein-protein Interactions

Angew. Chem. Int. Ed. 46, 3051-3054

42. C. Lin, Y. Liu, and H. Yan

Self-assembled Combinatorial Encoding Nanoarrays for Multiplexed Biosensing

Nano Lett. 7, 507-512 (2007).

41. J. Sharma, R. Chhabra, H. Yan, and Y. Liu

pH-driven Conformational Switch of “i-motif” DNA for Reversible Assembly of Gold Nanoparticles.

Chemical Communication 477-479 (2007)

2006

40. C. Lin, M. Xie, J. Chen, Y. Liu, and H. Yan

Rolling Circle Amplification of a DNA Nano- junction

Angew. Chem. Int. Ed. 45, 7537-7539 (2006).

This paper was chosen by the editors as “Hot Paper”: http://www3.interscience.wiley.com/cgi-bin/jabout/26737/2002_hotpaper.html

39. C. Lin, E. Katilius, Y. Liu, and H. Yan

Self-assembled Signaling Aptamer Nanoarrays for Protein Detection

Angew. Chem. Int. Ed. 45, 5296-5301 (2006).

38. C. Lin, Y. Liu, S. Rinker, and H. Yan

DNA Tile Based Self-assembly: Building Complex Nano-architectures

ChemPhysChem 7, 1641-1647 (2006).

37. K. Lund, Y. Liu, and H. Yan

Combinatorial Self-assembly of DNA Nanostructures

Organic and Biomolecular Chemistry 4, 3402-3403 (2006)

36. S. Rinker, Y. Liu, and H. Yan

Two Dimensional LNA/DNA Arrays: Estimating the Helicity of LNA/DNA Hybrid Duplex

Chemical Communication 2675-2677 (2006).

35. R. Chhabra, J. Sharma, Y. Liu, and H. Yan

Addressable Molecular Tweezers for DNA Templated Coupling Reactions

Nano Lett. 6, 978-983 (2006).

34. L. Lin, H. Wang, Y. Liu, H. Yan, and S. Lindsay

Recognition Imaging with a DNA Aptamer

Biophysical J. 90, 4236-4238 (2006).

33. K. Lund, B. Williams, Y. Ke, Y. Liu, and H. Yan

DNA Nanotechnology: a Rapidly Evolving Field

Current Nanoscience 2, 113-122 (2006).

32. Y. Ke, Y. Liu, J. Zhang, and H. Yan

A Study of DNA Tube Formation Mechanisms Using 4-, 8- and 12-Helix DNA Nanostructures

J. Am. Chem. Soc. 128, 4414-4421 (2006).

31. J. Zhang, Y, Liu, Y. Ke, and H. Yan

Periodic Square-like Gold Nanoparticle Arrays Templated by a DNA Nanogrids on a Surface

Nano Lett. 6, 248-251 (2006).

30. H. Yan and B. Xu

Towards Rapid DNA Sequencing: Detecting Single-Stranded DNA with a Solid-State Nanopore

Small 2, 310-312 (2006).

29. J. Sharma, R. Chhabra, Y. Liu, Y. Ke, and H. Yan

DNA Templated Self-assembly of Two-Dimensional and Periodical Gold Nanoparticle Arrays

Angew. Chem. Int. Ed. 45, 730-735 (2006).

2005

28. K. Lund, Y. Liu, S. Lindsay, and H. Yan

Self-assembling Molecular Pegboard

J. Am. Chem. Soc.127, 17606-17607 (2005).

27. Y. Liu, Y. Ke, and H. Yan

Self-assembly of Symmetric Finite Size DNA Nanoarrays

J. Am. Chem. Soc. 127, 17140-17141 (2005).

26. Y. Liu, C. Lin, H. Li, and H. Yan

Aptamer Directed Self-assembly of Proteins on a DNA Nanostructure

Angew. Chem. Int. Ed. 44, 4333 (2005).

25. S. H. Park, P. Yin, Y. Liu, J. Reif, T. H. LaBean, and H. Yan

Programmable DNA Self-assemblies for Nanoscale Organization of Ligands and Proteins

Nano Lett. 5, 729 (2005).

24. S. H. Park, R. Barish, H. Li , J. H. Reif , G. Finkelstein, H. Yan, and T. H. LaBean

Three Helix Bundle DNA Tiles Self-assemble into 2D Lattice or 1D Templates for Silver Nanowires

Nano Lett. 5, 693 (2005).

23. Y. Liu, and H. Yan

Modular Self-assembly of DNA Lattice with Tunable Periodicity

Small 1,327-330 (2005).

22. J. H. Reif, T. H. LaBean, S. Sahu, H. Yan and P. Yin

Design, Simulation, and Experimental Demonstration of Self-assembled DNA Nanostructures and Motors. In: UPP2004, LNCS 3566, ed. by J.P. Banatre, Springer-Verlag Berlin Heidelberg

pp. 173-187, (2005).

21. N.C. Seeman, B. Ding , S. Liao , T. Wang, W.B. Sherman, P.E. Constantinou, J. Kopatsch, C. Mao, R. Sha, F. Liu, H. Yan and P.S. Lukeman

Experiments in Structural DNA Nanotechnology: Arrays and Devices

Proc. SPIE; Nanofabrication: Technologies, Devices and Applications 5592, 71-81 (2005).

20. Sha, R., Zhang, X., Liao, S., Constantinou, P.E., Ding, B., Wang, T., Garibotti, A.V., Zhong, H., Israel, L.B., Wang, X., Wu, G., Chakraborty, B., Chen, J., Zhang, Y., Mao, C., Yan, H., Kopatsch, J., Zheng, J., Lukeman, P.S., Sherman, W.B. and Seeman, N.C.

Motifs and Methods in Structural DNA Nanotechnology, Proc. Intl. Conf. Nanomaterials, NANO 2005, July 13-15, 2005, Mepco Schlenk Engineering College, Srivakasi, India, V. Rajendran, ed.

pp. 3-10 (2005).

19. R. Sha, X. Zhang, S. Liao, P. Constantinou, B. Ding, T. Wang, A. V. Garibotti, H. Zhong, L. B. Israel, X. Wang, G. Wu, B. Chakraborty, J. Chen, Y. Zhang, H. Yan, Z Shen, W. SHen, P.Sa-Ardyen, J. Kopatsch, J. Zheng, P. Lukeman, W.B. Sherman, C. Mao, N. Jonoska, and N. C. Seeman

Structural DNA Nanotechnology: Molecular Construction and Composition. In: UC2005, LNCS 3699, ed. by C.S. Calude et al. Springer-Verlag Berlin Heidelberg

pp. 20-31 (2005).

2004

18. H. Yan

Nucleic Acid Nanotechnology

Science

17. S.H. Park, H. Yan, J.H. Reif, T. H. LaBean, and G. Finkelstein

Electronic Nanostructures Templated on Self-assembled DNA Scaffold

Nanotechnology 15, S525-S527 (2004).

16. H. Yan, P. Yin, S. H. Park, H. Li, L. Feng, X. Guan, D. Liu, J. H. Reif, and T. H. LaBean

Self-Assembled DNA Structures for Nanoconstruction

AIP Proceedings 725 (DNA-Based Molecular Electronics), 43-52. (2004).

15. P. Yin, H. Yan, X.J. Guan, A.J. Turberfield, and J. H. Reif

An Autonomous Unidirectional DNA Walker

Angew. Chem. Int. Ed. 43, 4906-4911 (2004).

14. H. Li, S. H. Park, J. H. Reif, T. H. LaBean, and H. Yan

DNA Templated Self-Assembly Of Protein And Nanoparticle Linear Arrays

J. Am. Chem. Soc. 126, 418 (2004).

13. Z. Shen, H. Yan, T. Wang, and N. C. Seeman

Paranemic Crossover DNA: A Generalized Holliday Structure with Applications in Nanotechnology

J. Am. Chem. Soc. 126, 1666 (2004).

2003

12. H. Yan, L. Feng, T. H. LaBean, and J. H. Reif

Parallel Molecular Computation of Pair-wise Exclusive-Or (XOR) Using DNA “String Tile” Self-Assembly

J. Am. Chem. Soc. 125, 14246 (2003).

11. H. Yan, S. H. Park, G. Finkelstein, J. H. Reif and T. H. LaBean

DNA Templated Self-assembly of Protein Arrays and Highly Conductive Nanowires

Science, 301, 1882 (2003).

Featured in Technology Research News, TRNMag.com: DNA forms nano waffles (http://www.trnmag.com/Stories/2003/102203/DNA_forms_nano_waffles_102203.html)

10. L. Feng, S. H. Park, J. H. Reif, and H. Yan

A Two-State DNA Lattice Switched By DNA Nanoactuator

Angew. Chem. Int. Ed. 42, 4342 (2003).

Featured by an interview with BBC radio program Discovery Today (Oct. 29, 2003). Editor’s choice of Science magazine, MATERIALS SCIENCE: DNA Makes a Move (http://www.sciencemag.org/content/vol302/issue5642/twil.shtml).

9. H. Yan, T. H. LaBean, L. Feng, and J. H. Reif

Directed Nucleation Assembly of DNA tile Complexes for Barcode Patterned Lattices

Proc. Natl. Acad. Sci. U.S.A. 100, 8103 (2003).

Featured in Technology Research News, TRNMag.com: DNA makes nano barcode (http://www.trnmag.com/Stories/2003/070203/DNA_makes_nano_barcode_070203.html)

8. H. Yan and N. C. Seeman

Edge-Sharing DNA Triangles And One-Dimensional Self-Assembly

J. Supramol. Chem., 1, 229-237 (2003).

2002

7. X. Zhang, H. Yan, Z. Shen and N. C. Seeman

Paranemic Cohesion of Topologically-Closed DNA Molecules, J. Am. Chem. Soc. 124, 12940-12941 (2002).

6. H. Yan, X. Yang, Z. Shen and N. C. Seeman

A Robust Sequence-dependent Rotary DNA Device

Nature, 415, 62-65 (2002).

2000

5. T. H. LaBean, H. Yan, J. Kopatsch, F. Liu, E. Winfree, J. H. Reif and N. C. Seeman

The Construction, Analysis, Ligation and Self-assembly of DNA Triple Crossover Molecules*

J. Am. Chem. Soc. 122, 1848-1860 (2000).

1998

4. N.C. Seeman, H. Wang, X. Yang, F. Liu, C. Mao, W. Sun, L. Wenzler, Z. Shen, R. Sha, H. Yan, M.H. Wong, P. Sa-Ardyen, B. Liu, H. Qiu, X. Li, J. Qi, S.M. Du, Y. Zhang, J.E. Mueller, T.-J. Fu, Y. Wang, and J. Chen

New Motifs in DNA Nanotechnology

Nanotechnology 9, 257-273 (1998).

1996

3. Y. Ma, Q. Wang, H. Yan, X. Ji and Q. Qiu

Zeolite-Catalyzed Esterification. Synthesis of Acetates, Benzoates And Phthalates

Appl. Catal. 139, 51-57 (1996).

2. Q. Wang, Y. Ma, X. Ji, H. Yan, and Q. Qiu.

Zeolite-Catalyzed Friedel-Crafts Acylation of Aromatics. Synthesis Of 4-Acyl Anisole With A HY Catalyst

Chin. Chem. Lett. 7, 99-102 (1996)

1995

1. Q. Wang, Y. Ma, X. Ji, H. Yan and Q. Qiu

Regioselective Acylation of Anisole with Carboxylic-Acid Over HZSM-5 Catalyst

J. Chem. Soc. Chem. Comm. 22, 2307-2308 (1995).

Book Chapters

1. N.C. Seeman, J. Chen, Y. Zhang, B. Liu, H. Qiu, T.-J. Fu, Y. Wang, X. Li, X. Yang, J. Qi, F. Liu, L.A. Wenzler, S, Du, J.E. Mueller, H. Wang, C. Mao, W. Sun, Z. Shen, M.H. Wong, H. Yan and R. Sha.
“A Bottom-Up Approach to Nanotechnology Using DNA”, In: Biological Molecules in Nanotechnology
ed. by S.C. Lee, IBC Libraries, Southborough, MA, Chapter 8 (1998).

2. N.C. Seeman, C. Mao, F. Liu, R. Sha, X. Yang, L. Wenzler, X. Li, Z. Shen, H. Yan, P. Sa-Ardyen, X. Zhang, W. Shen, J. Birac, P. Lukeman, Y. Pinto, J. Qi, B. Liu, H. Qiu, S.M. Du, H. Wang, W. Sun, Y. Wang, T.-J. Fu, Y. Zhang, J.E. Mueller and J. Chen.
“Nicks, Nodes, and New Motifs for DNA Nanotechnology”. In: Frontiers of Nano-Optoelectronic Systems
ed. by L. Pavesi & E. Buzanova, Kluwer, Dordrecht, 177-198 (2000).

3. M. Stojacovic, T. LaBean, and H. Yan
“Computing with Nucleic Acids”. In: Bioelectronics, From Theory to Applications
ed. by I. Willner, Weily VCH, 2005. ISBN: 3-527-30690-0

4. H. Yan and Y. Liu
“DNA Nanotechnology: An Evolving Field”. In: Nanotechnology: Science and Computation
ed. by J. Chen, N. Janoska, G. Rozenberg, Springer, 2005, ISBN: 3-540-30295-6.

5. R. Chhabra, J. Sharma, Y. Liu, and H. Yan
“Patterning Metallic Nanoparticles by DNA Scaffolds”. In: Bio-Applications of Nanoparticles
ed. by W. Chan, Landes Bioscience, 2007. Pp. 107-115 (chapter 8).

6. B. Ding, Y. Liu, S. Rinker, and H. Yan
“DNA-Templated Self-assembly of Protein Arrays and Highly Conductive Nanowires”. In: Encyclopedia of Complexity and System Science
ed. by D. Bonchev, Springer, (2008).

7. J. D. Carter, C. Lin, Y. Liu, H. Yan and T. H. LaBean
“DNA-based Self-assembly of Nanostructures”. In: Frontiers in Nanoscience and Nanotechnology
ed. by A.Narlikar and Y. Fu, Oxford University Press, (2009).

8. Y. Ke, Y. Liu, and H. Yan
“Structural DNA Nanotechnology: Information Guided Self-assembly”. In: Advanced Nanomaterials
ed. by K. E. Geckeler, Wiley-VCH, (2009).

9. J. Sharma, Y. Liu, and H. Yan
“Structural DNA Nanotechnology: Information Guided Self-assembly”. In: Chemistry of Nanostructured Materials
ed. by P. Yang, World Scientific Publisher, 2011.

10. A. Edwards and H. Yan
“DNA Origami”. In: Nucleic Acid Nanotechnology
ed. by K. Gothelf, Springer, 2013.

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