Yan Lab · Arizona State University

Programming
Matter at the
Molecular Scale

We design DNA and RNA structures that assemble, compute, and function—unlocking new possibilities in medicine, materials, and molecular engineering.

The PI

Prof. Hao Yan, Ph.D.

Dr. Hao Yan is Regents Professor and Milton D. Glick Distinguished Professor of Chemistry and Biochemistry at Arizona State University, where he also serves as Director of the Biodesign Center for Molecular Design and Biomimetics. He is known for pioneering contributions to structural DNA nanotechnology, with research spanning three areas: achieving atomic-level precision in structural design through DNA crystal engineering, developing complex architectures using DNA and RNA origami, and expanding functional capabilities in nucleic acid nanotechnology. He received his B.S. in chemistry from Shandong University in 1993 and his Ph.D. from New York University in 2001, followed by research at Duke University before joining ASU in 2004. Dr. Yan has authored over 240 scientific publications, holds more than 50 patents, and has co-founded two biotechnology companies. He is a Fellow of the American Association for the Advancement of Science (AAAS), the American Institute for Medical and Biological Engineering (AIMBE), the National Academy of Inventors (NAI), the European Academy of Sciences (EurASc), and the European Academy of Sciences and Arts (EASA). His honors include the Feynman Prize in Nanotechnology, the Rozenberg Tulip Award in DNA Computing, the Humboldt Research Award, the Sloan Research Fellowship, among many others.

Research

Research Pillars

Design

Our research focuses on designing programmable DNA nanostructures by encoding...

Assembly

We investigate how nucleic acid nanostructures form, evolve, and organize...

Functionalization

We explore DNA nanostructures as programmable scaffolds for organizing functional...

Interface

Our research develops DNA and RNA nanostructures as programmable interfaces...

OUR TEAM

Meet Our People

Dr. Hao Yan

Position: Principal Investigator
Email: [email protected]

Biomolecular Designer and Programmer

Dr. Hao Yan

Principal Investigator

Biomolecular Designer and Programmer

Chad R Simmons

Position: Academic Professional
Email: [email protected]

Biomacromolecular Crystallographer

Chad R Simmons

Academic Professional

Biomacromolecular Crystallographer

Dr. Yang Xu

Position: Assistant Research Professor
Email: [email protected]

Biomolecular Therapeutics and Diagnostics

Dr. Yang Xu

Assistant Research Professor

Biomolecular Therapeutics and Diagnostics

Dr Kun Dai

Position: Assistant Research Scientist
Email: [email protected]

Nucleic Acid Biologics

Dr Kun Dai

Assistant Research Scientist

Nucleic Acid Biologics

Abhay Prasad

Position: 5th Year PhD Candidate
Email: [email protected]

Postdoc Associate

Abhay Prasad

5th Year PhD Candidate

Postdoc Associate

Rong Zheng

Position: 4th Year PhD Candidate
Email: [email protected]

Postdoc Associate

Rong Zheng

4th Year PhD Candidate

Postdoc Associate

Lanshen Zhao

Position: 5th Year Graduate Student
Email: [email protected]

Diaganostics and Cancer Therapy

Lanshen Zhao

5th Year Graduate Student

Diaganostics and Cancer Therapy

Xinyi Tu

Position: 5th Year Graduate Student
Email: [email protected]

RNA/DNA nanotechnology for Cancer Therapy

Xinyi Tu

5th Year Graduate Student

RNA/DNA nanotechnology for Cancer Therapy

Thong Diep

Position: 4th Year PhD Candidate
Email: [email protected]

Finite size DNA lattice

Thong Diep

4th Year PhD Candidate

Finite size DNA lattice

Aleksandra Petrova

Position: 3rd Year PhD Candidate
Email: [email protected]

RNA Nanomedicine

Aleksandra Petrova

3rd Year PhD Candidate

RNA Nanomedicine

Gengshi Wu

Position: 3rd Year PhD Candidate
Email: [email protected]

RNA Nanotechnology Design and Assembly

Gengshi Wu

3rd Year PhD Candidate

RNA Nanotechnology Design and Assembly

Yichen Yan

Position: 2nd Year PhD Candidate
Email: [email protected]

Nucleic Acid Biology

Yichen Yan

2nd Year PhD Candidate

Nucleic Acid Biology

Xiang Gu

Position: 1st Year PhD Candidate
Email: [email protected]

DNA Nanotechnology

Xiang Gu

1st Year PhD Candidate

DNA Nanotechnology

Lihui Wang

Position: 1st Year PhD Candidate
Email: [email protected]

DNA Nanotechnology

Lihui Wang

1st Year PhD Candidate

DNA Nanotechnology

Shreya Raha

Position: 1st Year PhD Candidate
Email: [email protected]

DNA Nanotechnology

Shreya Raha

1st Year PhD Candidate

DNA Nanotechnology

Publications

Featured Publications

Listen to our DNA Nano Song

Support Our Science

Biodesign Center for Molecular Design and Biomimetics

Transforming Human Health Through Molecular Design

Reimagining the Future of Medicine–One Molecule at a Time

Every great medical revolution begins with a single transformative idea – an innovation that changes how we understand, detect, and treat disease.

At the Biodesign Center for Molecular Design and Biomimetics (BCMDB), part of Arizona State University’s Biodesign Institute, Scientists are building medicine from the molecule up – engineering DNA, RNA, proteins, and peptides into programmable systems that can:

– Detect diseases before symptoms appear
– Deliver therapies precisely where needed
– Neutralize pathogens and tumors with accuracy
– Activate the body’s own healing power

This is the frontier of programmable molecular medicine, where design meets discovery and innovation meets healing.

Biodesign Center for Molecular Design and Biomimetics

contact info

1001 S McAllister Ave, Tempe, Az, 85287
Phone: 480.727.8570
Fax: 480.965.2747
Copyright © 2026 Hao Yan – All Rights Reserved.